The immunology of multiple sclerosis - Nature Reviews Immunology
WEBMay 4, 2022 · This Review explores the complex roles of immune cells in the onset and progression of multiple sclerosis, describing the influence of environmental and genetic factors on immune cell...
Immunopathology of multiple sclerosis | Nature Reviews Immunology
WEBAug 7, 2015 · Two decades of clinical experience with immunomodulatory treatments for multiple sclerosis point to distinct immunological pathways that drive disease relapses and progression.
Current and Future Immunotherapies for Multiple Sclerosis
WEBMultiple sclerosis (MS) is a complex autoimmune disease characterized by inflammation of the central nervous system (CNS). It is caused by immune cells that attack components of the myelin sheath surrounding the neuronal axons of the nerves, resulting in demyelination and neurologic dysfunction.
The Immune Response in Multiple Sclerosis - PubMed
WEBJan 24, 2022 · Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, and neurodegenerative disease that affects the central nervous system (CNS). MS is characterized by immune dysregulation, which results in the infiltration of the CNS by immune cells, triggering demyelination, axonal damage, and neurodeg ….
The immunology of multiple sclerosis - PubMed
WEBRecent studies explore the role of immune cells at different stages of MS and how they interact with cells of the central nervous system (CNS). The findings presented here begin to question the exclusivity of an antigen-specific cause and highlight how seemingly distinct immune cell types can share common functions that drive disease.
WEBMay 4, 2022 · progression of multiple sclerosis (MS) limits our ability to effectively treat this complex neurologi-cal disease. Recent studies explore the role of immune cells at different stages of MS and...
Multiple sclerosis and the role of immune cells - PMC
WEBAug 8, 2014 · Multiple sclerosis (MS) is a complex disease with many different immune cells involved in its pathogenesis, and in particular T cells as the most recognized cell type. Recently, the innate immune system has also been researched for its effect on the disease.
Multiple Sclerosis: Mechanisms and Immunotherapy - Cell Press
WEBMultiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) of presumed autoimmune etiology. Our understanding of the immune processes that contribute to MS has led to FDA-approved, disease-modifying drugs that are effective in relapsing forms of MS.
Immunopathology of multiple sclerosis - PubMed
WEBSep 15, 2015 · Two decades of clinical experience with immunomodulatory treatments for multiple sclerosis point to distinct immunological pathways that drive disease relapses and progression. In light of this, we discuss our current understanding of multiple sclerosis immunopathology, evaluate long-standing hypoth ….
The immuno-pathophysiology of multiple sclerosis - PMC
WEBThe role of T lymphocytes in multiple sclerosis. The lymphocytic presence within plaques and bordering areas suggests that inflammatory destruction in MS is driven by antigen-specific targeting of myelin and other CNS components.