Pulmonary Vascular Remodeling in Pulmonary Hypertension
WEBPulmonary vascular remodeling is the key structural alteration in pulmonary hypertension. This process involves changes in intima, media, and adventitia, often with the interplay of inflammatory cells. We review the pathology of these changes and highlight some of the pathogenetic mechanisms that underlie the remodeling process.
Vascular Remodeling in Pulmonary Arterial Hypertension: The …
WEBDec 22, 2021 · Schematic overview of some of the different immunological mechanisms involved in vascular remodeling in pulmonary arterial hypertension (PAH).
Pulmonary Vascular Remodeling in Pulmonary Hypertension
WEBFeb 19, 2023 · Pulmonary vascular remodeling involves the proliferation and phenotypic transformation of pulmonary artery endothelial cells (PAECs) and pulmonary artery smooth muscle cells (PASMCs) of the middle membranous pulmonary artery, as well as complex interactions involving external layer pulmonary artery fibroblasts (PAFs) and extracellular matrix (ECM).
Molecular mechanisms of pulmonary arterial remodeling
WEBApr 22, 2014 · The purpose of this review is to provide updated information on molecular mechanisms involved in pulmonary arterial remodeling with a focus on growth factors, transcription factors, and epigenetic pathways in PASMC proliferation.
Pulmonary Vascular Remodeling in Pulmonary Hypertension
WEBFeb 19, 2023 · Pulmonary vascular remodeling is the critical structural alteration and pathological feature in pulmonary hypertension (PH) and involves changes in the intima, media and adventitia.
PDZ-Binding Kinase, a Novel Regulator of Vascular Remodeling in ...
WEBApr 29, 2024 · A defining feature of PAH is the inappropriate remodeling of pulmonary arteries (PA) leading to right ventricle failure and death. Although treatment of PAH has improved, the long-term prognosis for patients remains …
USP15 promotes pulmonary vascular remodeling in pulmonary …
WEBJan 12, 2023 · Pulmonary hypertension (PH) is a life-threatening cardiopulmonary disease characterized by pulmonary vascular remodeling. Excessive growth and migration of pulmonary artery smooth muscle cells...
Pulmonary vascular remodeling in pulmonary hypertension
WEBDec 26, 2016 · Pulmonary vascular remodeling is the key structural alteration in pulmonary hypertension and involves changes in the intima, media and adventitia, often with the interplay of inflammatory cells. This review examines the pathology of these changes and highlights some of the pathogenetic …
Global Pulmonary Vascular Remodeling in Pulmonary …
WEBDec 15, 2017 · We hypothesized that pulmonary venous hypertension in heart failure (HF) leads to predominate remodeling of pulmonary veins and that the severity of venous remodeling is associated with the severity of pulmonary hypertension (PH) in HF.
Pulmonary vascular remodeling in pulmonary hypertension
WEBPulmonary vascular remodeling is the key structural alteration in pulmonary hypertension and involves changes in the intima, media and adventitia, often with the interplay of inflammatory cells. This review examines the pathology of these changes and highlights some of the pathogenetic mechanisms th ….