Les Eyzies is a commune in the Dordogne department in Nouvelle-Aquitaine in southwestern France. It was established on 1 January 2…Les Eyzies is a commune in the Dordogne department in Nouvelle-Aquitaine in southwestern France. It was established on 1 January 2019 by merger of the former communes of Les Eyzies-de-Tayac-Sireuil, Manaurie and Saint-Cirq. Les Eyzies station has rail connections to Périgueux and Agen.