Antwerp is a city and a municipality in the Flemish Region of Belgium. It is the capital and largest city of Antwerp Province, and the third largest …Antwerp is a city and a municipality in the Flemish Region of Belgium. It is the capital and largest city of Antwerp Province, and the third largest city in Belgium by area at 204.51 km² after Tournai and Couvin. With a population of 536,079, it is the most populous municipality in Belgium, and with a metropolitan population of over 1.2 million people, the country's second-largest metropolitan area after Brussels.