Midland is a city in the U.S. state of Texas and the seat of Midland County with small portions extending into Martin County. The population wa…Midland is a city in the U.S. state of Texas and the seat of Midland County with small portions extending into Martin County. The population was 132,524 as of the 2020 census. Located in the Permian Basin in West Texas, Midland is a major center for American oil and natural gas production.