The Lions had a 17-point lead over the 49ers last year in the NFC championship game but squandered the lead and team's ...

The San Francisco 49ers are prepping for Week 17 against the Detroit Lions on Monday Night Football. What they're not ...

Which team will win the Monday Night Football game? Check out these NFL Week 17 picks and NFL Week 17 predictions ...

The Detroit Lions could clinch the No. 1 seed in the NFC on Monday Night Football against the San Francisco 49ers, and you ...

If the Vikings lose on Sunday to the Packers, the Lions can seize the No. 1 seed with a Monday night win over the 49ers.

The last time the Detroit Lions played at Levi’s Stadium, they endured a heartbreaking 34-31 loss to the San Francisco 49ers in the NFC title game last season. When the teams meet again next Monday in ...

The Seattle Seahawks kept their postseason hopes alive by defeating the Chicago Bears but remain on the outside looking in.

Dan Campbell explained why he won't rest any Lions starters for Detroit's "Monday Night Football" matchup with the San ...

The San Francisco 49ers are 6-9 and out of playoff contention, but beat the Detroit Lions in the NFC championship game in ...

On the fifth day of the 17th Week, the NFL gave the people the Detroit Lions and the San Francisco 49ers. The league had more of an NFC Championship level of a matchup in mind with this one. However, ...

San Francisco 49ers Head coach Kyle Shanahan provided updates on LB Dre Greenlaw's game status and shared a scouting report on the Detroit Lions. San Francisco 49ers ... the team's performance on ...

If you have a valid cable login, you can stream tonight’s game on ESPN, Watch ESPN, ABC, ABC.com, or the ESPN app. You can also watch with an active subscription to DirecTV Stream, fuboTV , Hulu + ...