May potentiate CYP3A substrates (eg, triazolam, midazolam, statins [rhabdomyolysis], sildenafil [reduce dose of sildenafil], colchicine [reduce starting dose of colchicine, max dose should be ...

"Whether longer treatment with colchicine, higher doses, or a larger cohort would improve pain and function or modify radiographic progression remains to be determined," the authors write.

Reduce colchicine dose if coadministration is necessary. Hypoglycemia with oral hypoglycemics/insulin; carefully monitor glucose. Oral anticoagulants: frequently monitor INR and prothrombin times.

Jan Cornel and C. Michael Gibson Discuss: LoDoCo2 Low-Dose Colchicine in Coronary Disease. Receive the the latest news, research, and presentations from major meetings right to your inbox. TCTMD ® is ...

In the colchicine trial, Samuels said, the drug supplier lost access to the original 0.8-mg dose and had to substitute a dose of 0.6 mg partway through. Liu mentioned that the pandemic had ...

Colchicine, a cheap and readily available anti ... 2,500 patients who receive the usual standard of care on its own. Dosage used will be 1000 micrograms for the first treatment, then 500 ...

DISCUSSION: Fatal outcomes are possible even with colchicine doses less than 0.5 mg/kg. Physicians caring for colchicine-poisoned patients must be prepared for the possibility of acute ...