Data on patient demographics, cyclosporine dosages, dosage form, blood trough concentrations, clinical laboratory test values, and concurrent medications were collected. One-compartment models for ...

Restasis (cyclosporine) is a brand-name drug that’s prescribed for chronic dry eye in adults and certain children. Restasis comes as an eye drop solution. The typical dosage is one drop per ...

The Prosthetic Replacement of Ocular Surface Ecosystem was well-tolerated and appeared efficacious as a delivery system for ...

Use lowest effective dose. Pregnancy. Nursing mothers: not recommended. Potentiated by CYP3A4 inhibitors (eg, ketoconazole, macrolides), cyclosporine, estrogens. Antagonized by CYP3A4 inducers (eg ...

Use lowest effective dose. Pregnancy. Nursing mothers: not recommended. Potentiated by CYP3A4 inhibitors (eg, ketoconazole, macrolides), cyclosporine, estrogens. Antagonized by CYP3A4 inducers (eg ...

The relief in discomfort lasted up to 9 minutes after instillation. Cold instillation of a cyclosporine A solution reduced instillation discomfort among patients with dry eye disease, with results ...

Using genetic markers to adjust initial doses of cyclosporine or tacrolimus may prove difficult, considering the variety of polymorphisms known to affect CYP3A4, CYP3A5, and MDR1. The current ...