The heart is a powerful pump made of muscle (myocardium). It is divided into four chambers: the upper two atria are the receiving chambers and the lower two ventricles are the pumping chambers.

Affinia Therapeutics ("Affinia"), an innovative gene therapy company with a pipeline of rationally designed adeno-associated ...

All three brothers were diagnosed with dilated cardiomyopathy, or DCM, a serious condition in which the muscles of the heart weaken and expand, compromising the organ’s ability to pump blood.

and a pre-clinical program targeting BAG3-associated dilated cardiomyopathy (DCM), a heart failure condition that causes ...

Dilated cardiomyopathy (DCM) is a heterogeneous disorder that is familial in approximately 30% of cases. Although several genes have been identified that can cause familial DCM, molecular analyses ...