cerevisiae lost the key enzymes needed for RNAi and thus this pathway. Finally, the work has implications for organisms where Dicer, and indeed an RNAi pathway, have yet to be found, given that ...

In 2002, on the heels of the discovery that RNA interference existed in human cells, the usually reserved journal Science proclaimed RNAi the "breakthrough of the year." Here was a part of the ...

Slicer Dicer is a powerful, self-service data exploration tool integrated into Drexel’s Epic system, designed to support researchers in their data-driven projects. To begin using Slicer Dicer, simply ...

The longer form of the RNA produced from a microRNA gene acts as a precursor. It's able to fold over and base-pair with itself, forming a structure called a hairpin. An enzyme called Dicer ...

Sometimes, double-stranded RNA is cut into smaller fragments called ... These genes create enzymes called dicer-like 2 and ...

The strategy adopted by the project partners involves the use of customized double-stranded ... enzyme called 'Dicer' chops it into smaller segments known as small interfering RNA (siRNA).

The research team tested the activity of over 2,600 different RNA sequences predicted to belong to a class of RNA enzymes called "twister ribozymes," which have the ability to cut themselves in two.

See how small bits of non-coding RNA target mRNA for destruction and regulate gene expression. Evidence has also shown that siRNA is involved in antiviral defense in certain plant and animal species.

The Nintendo DS played a huge part in my teen years, providing much more complex games and experiences than its predecessor, the Game Boy Advance. However, I’ve since moved to a different ...

Gene silencing by the tRNA maturase tRNase ZL under the direction of small-guide RNA. Gene Therapy, Vol. 14, Issue. 1, p. 78. Gómez, Isaura Torres Ruiz, Orville Hernandez Muñoz, Jose F. Garcia, Ana ...

For a molecule of RNA, the world is a dangerous place. Unlike DNA, which can persist for millions of years in its remarkably stable, double-stranded form, RNA isn’t built to last—not even ...

After translation of the viral proteins that are necessary to establish the viral-replication machinery, viral RNA replication begins (Figure 1). Similar to other positive-strand RNA viruses ...