Second, the potential of endogenous stem cells present in the mammalian nervous system can be harnessed and expanded to repair damaged tissue. It is increasingly clear that endogenous stem cells ...

We provide: stereotaxic and other surgical engrafting of ESC, iPSC, ASC and cancer stem cells into mice and other model systems in vivo gene transfer into endogenous stem cells in brain, heart and ...

“I was very enthusiastic about Fate's approach to regenerative medicine: modulating endogenous stem cells,” he explains. “While working at Genetics Institute, I had seen the power of this ...

Diamond-Blackfan anemia (DBA) is a rare, life-threatening genetic blood disorder. It impairs the bone marrow's ability to ...

Stem cells have traditionally been characterized ... perhaps due to competition with endogenous host cells. In this case, transdifferentiation would be observed only under conditions of host ...

"The SVZ stem cell niche is a fragile system ... this will bring us closer to promote the endogenous repair of the brain in ...

This work is an important contribution to understanding the role of FGF signaling in the induction of primitive-like cells in a 2D system of human gastrulation. The authors provide compelling evidence ...

"The SVZ stem cell niche is a fragile system ... this will bring us closer to promote the endogenous repair of the brain in central nervous system disorders," says Schachtrup.

Heart muscle cells grown from stem cells show promise in monkeys with a heart problem that typically results from a heart ...

We will discuss the biological foundation and current applications of stem cells, focusing on two specific areas: endogenous neural stem cells and their capacity to repair injury, and myelinating ...