NNRTIs bind to a hydrophobic pocket near the catalytic site of HIV-1 RT and inactivate enzymatic activity. NNRTI-resistance mutations & their mechanism of drug resistance The most prevalent NNRTI ...

The same mutation that confers HIV resistance to some Ashkenazi Jews also puts them at higher risk of dying from West Nile fever, which is more prevalent in Israel than in the north European ...

Some mutations occur in the parts of HIV which are targeted by anti-HIV medications. This can result in strains of HIV developing that are less easily controlled by the drugs. These HIV strains are ...

Indirect measurement of drug resistance: results regarding mutations must be subjectively ... Can be used to evaluate non-B clade HIV-1 strains not commonly found in the United States Lack of ...

A significant breakthrough in treating the Human Immunodeficiency Virus (HIV) came recently with the US Federal Drug ...

For the reports involving oral PrEP, genetic testing of the HIV acquired in all but one breakthrough case detected mutations associated with resistance to emtricitabine, tenofovir, or both. For ...

Now new laboratory work in Canada sheds light on the vulnerabilities of HIV's pockets of resistance in the body, and potential ways to thwart them. Led by Université de Montréal medical ...

Though the number of individuals detected to have this specific mutation is relatively low compared to the number of HIV patients worldwide ... evolution, drug resistance, and vaccine efficacy.

He had been searching for years for genetic changes that conferred HIV resistance ... as if a person had naturally inherited the mutation. This discovery has not yet translated into new treatments.