A new gene therapy can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the heart can pump and dramatically improves ...

Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns. Fortunately ...

Researchers from the Bakkers group at the Hubrecht Institute have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in ...

"We know that in heart failure from many causes ... The researchers then conducted several tests, starting with a mouse model in which the CMYA5 gene was knocked out. The mice showed ...

Mouse Models Exist for Many Human Genetic Diseases ... These diseases include several types of cancer, heart disease, hypertension, metabolic and hormonal disorders, diabetes, obesity ...

2024 — Researchers have reduced scar formation and improved heart function in mouse models of heart failure using a monoclonal antibody treatment, similar to that approved by the FDA to treat other ...

Hypertrophic cardiomyopathy (HCM) is a prevalent inherited cardiac disease marked by left ventricular hypertrophy, often due ...