Three subunits of the IL-2 receptor are available — α chain (CD25), β chain (CD122) and γ chain (CD132). IL-2 and IL-15 receptor complexes share the β and γ chains, and the γ chain is used ...

It is triggered by antibodies that attack an enzyme called MDA5 (melanoma differentiation-associated protein 5) – an RNA ...

In a report released today, Paul Matteis from Stifel Nicolaus maintained a Buy rating on Neurogene (NGNE – Research Report), with a price ...

T-cell therapy is a revolutionary immunotherapy approach in which T cells are genetically modified to express a receptor that ...

Its lead product candidate, NL-201, is a combined IL-2 and IL-15 agonist designed to eliminate alpha receptor binding. The company was founded by Daniel-Adriano Silva, Carl Walkey, and Umut Ulge in ...

AnaptysBio (NASDAQ:ANAB – Get Free Report) had its price objective lifted by UBS Group from $23.00 to $33.00 in a research ...

Another example is engineering T cells to express cytokines like IL-12, which enhances their ability to target and kill ...

Our pipeline also includes a preclinical candidate NKTR-0165, which is a bivalent tumor necrosis factor receptor type II agonist antibody. Nektar, together with various partners, is also evaluating ...

MyD88 is a receptor-proximal adapter protein that apparently mediates signal transduction by all members of the Toll and IL-1 receptor family. Therefore, MyD88-dependence, although strongly ...

These findings suggest that KIR2DS2-positive (KIR2DS2+) natural killer (NK) cells could be an attractive therapeutic target ...

HC Wainwright reissued their neutral rating on shares of Zura Bio (NASDAQ:ZURA – Free Report) in a report released on Monday ...