Symptoms of JME usually begin in adolescence. JME causes myoclonic, generalized tonic-clonic, and absence seizures. These seizures can cause jerking movements, convulsions, or periods of blank ...

these agents improved the patient's myoclonus and the frequency of her status epilepticus, but the tonic–clonic seizures and head drops persisted. In the following months, the patient's mental ...

A study published in 2013 discovered that while VNS was effective in lowering the incidence of some types of seizures (tonic-clonic and myoclonic type), it was ineffective at reducing atonic or ...

Myoclonic (≥12yrs), tonic-clonic (≥16yrs): initially 500mg twice daily; increase at 2-week intervals in increments of 1g/day to target dose of 3g/day. Renal impairment: CrCl 50–80mL/min ...

Myoclonic: ≥12yrs: initially 500mg twice daily; increase at 2-week intervals in increments of 1g/day to target dose of 3g/day. Tonic-clonic: ≥16yrs: initially 500mg twice daily; increase at 2 ...

drop seizures caused by myoclonus, and generalized tonic–clonic seizures that tended to occur as status epileptici. These phenomena persisted, despite pharmacological treatment with combinations ...