Solve Therapeutics Inc. has identified antibody-drug conjugates comprising an UC-961 antibody or a tyrosine-protein kinase transmembrane receptor ROR2 (ROR2)-targeting antibody covalently linked to ...
The cancer cells (magenta) lack the noncanonical Wnt receptor, Ror2. The protein fibronectin (orange) is up-regulated and assembled by Ror2-deficient tumor cells, triggering the invasion, ...
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