Several cell-surface molecules have been implicated in the early interactions of rotavirus with its host cell, including sialic acid, various integrins, heat shock protein 70 and gangliosides.
Researchers from Children's Hospital of Philadelphia (CHOP) found that transmission of rotavirus vaccine strains in a neonatal intensive care unit (NICU) is rare and without clinical consequences ...
Safer and more broadly effective rotavirus vaccines could be achieved if initial investigations 1 into the boosting effect of plant-derived virus-like particles hold up in further trials.