The San Francisco 49ers face slim odds of landing a top-nine pick in the 2025 NFL Draft. The Carolina Panthers and New York ...

The playoff-eliminated San Francisco 49ers are set to host the Detroit Lions on Monday night in a rematch of last season's ...

San Francisco 49ers top scorers look to capitalize on opportunities early against Detroit Lions stout defense.

Judges declare the 2020 conviction of the former NFL Defensive Player of the Year is ‘legally invalid’ after finding his race ...

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC Championship ...

Former NFL defensive tackle Dana Stubblefield’s rape conviction was overturned by an appellate court on Thursday, court documents show. The 54-year-old played in the NFL from 1993-2003, spending seven ...

President of football operations and general manager John Lynch is back at the drawing board. He revealed the 49ers’ general ...

Less than a year ago, the 49ers and the Lions were the two best teams in the NFC. Now the Lions are on the verge of locking up the no. 1 seed.

The San Francisco 49ers have become the latest team to suffer the dreaded Super Bowl hangover. After a 12-5 season and a ...

The San Francisco 49ers showed how to handle the challenges that arise when personal interests clash with team dynamics by ...

NFL Week 17 odds, picks, predictions, TV channel, streaming information for Monday Night Football game between Detroit Lions ...

The 49ers placed Williams (ankle) on injured reserve Thursday. Williams had missed San Francisco's past four ... a quadriceps injury during the team's Week 16 loss versus the Dolphins.