To explain his theory of the pathogenesis of serum sickness ... until circulating antibody has disappeared from the patient, the full reaction is not immediate, but “accelerated”.

Serum sickness resulting from the formation of complexes between anti-antibodies and the drug occurs ... Infusion-related reactions such as fever, chills, and other systemic effects occur in ...

who had also previously received infliximab (Remicade), had experienced serum sickness in response to adalimumab. The sixth patient with no prior history of medication reactions had previously ...