A figure from the paper shows that an siRNA delivered by a lipid nanoparticle was able to reduce expression of the protein PU.1 and other related markers (IBA1, C1q, GFAP) in the brains of mice.

Two start-ups have launched to develop next-generation drugs using small interfering RNA (siRNA) to silence genes. The first, Judo Bio, is a spin-off of the venture capital firm Atlas Venture.

In the midst of body image angst, people tend to forget about the body's important utility, and it does so much for us, too--our bodies get us from point A to point B, for example. Yet many people ...

The New England Journal of Medicine (NEJM) Images in Clinical Medicine article type captures and illuminates the sense of visual discovery and variety that physicians experience every day in ...

To overcome these barriers, many siRNA delivery systems have been developed. Among these, lipid-based nanoparticles have great potential owing to their biocompatibility and low toxicity in ...

Google Photos could soon display IPTC credit metadata on images, which will be helpful in figuring out if an image is AI-generated or not. The changes are not currently live within Google Photos ...

What's the best AI image generator? They may only be a few years old, but the world of genAI is fast-moving and these are our favorite apps out there right now. Like the best AI art generators ...

The company has designed a drug candidate that combines a ligand with small interfering RNA (siRNA) that should silence messenger RNA (mRNA) and, in turn, reduce certain solute carrier proteins ...

The US biotech has just reported phase 2 trial results with the small, interfering RNA (siRNA) gene-silencing drug showing that it an cause a 90% or greater reduction in Lp(a) levels – a risk ...

Insitro has teamed up with Eli Lilly to help power programs into the clinic, tapping the Big Pharma for an option on technology to deliver siRNA molecules it discovered using its machine learning ...

Welcome to the 3 rd Annual RNAi – Based Therapeutics Summit: Overcoming Barriers for Targeted siRNA Therapeutics Built with biopharmaceutical industry insights, this in person conference will ...

The firm's technology platforms include antibody, T cell, innate immunity and siRNA, which are designed to stimulate and enhance the immune system by exploiting critical observations of natural ...