Production of siRNA from a vector is predominantly done through the transcription of a shRNA that structurally mimics an miRNA precursor. This system allows integration of the shRNA cassette into ...

Ambion and Applied Biosystems (Foster City, California, USA) have developed 19 siRNA libraries ... in the context of a microRNA (miR) cassette, which they refer to as shRNA-miRs.

Various gene silencing technologies like siRNA, miRNA, ribozymes, DNAzymes have shown promise as therapeutics agents against viral diseases. RNAi-based drugs against viruses such as ebola virus ...

Preventing siRNA effects from spreading to unspecified areas of the brain will require the use of viral expression of shRNA- or miRNA-based constructs. It is crucial to identify the location of β ...

You can gain deeper understanding of expression patterns of small non-coding RNAs by using assays that retain spatial organization at single cell resolution. Traditional methods such as NGS, can ...

The Nobel Prize in Medicine was awarded on Monday to two US scientists for discovering microRNA, a previously unknown type of genetic switch which is hoped can pave the way for new medical ...

Two scientists have been award the 2024 Nobel Prize in Physiology or Medicine for their discovery of microRNA. Victor Ambros, professor of molecular medicine at the University of Massachusetts ...

The Nobel Committee announced on October 7 that the Nobel Prize for Medicine or Physiology would be shared by Victor Ambros and Gary Ruvkun “for the discovery of microRNA and its role in post ...

the facility has successfully completed a number of high-content miRNA, genome-wide siRNA and compound screens (see Publications). The imaging equipment within the facility also forms part of the AMIS ...

The Nobel Prize in medicine was awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA, molecules that help ...

How did you start thinking about this fundamental question at the heart of the discovery of microRNA, about how cells get the instructions to do what they do? The paper that described this ...

You can gain deeper understanding of expression patterns of small non-coding RNAs by using assays that retain spatial organization at single cell resolution. Traditional methods such as NGS, can ...