All-Pro tight end George Kittle will miss the San Francisco 49ers' game on Sunday against the Los Angeles Rams with a hamstring injury.

Ricky Pearsall was supposed to make his regular-season debut with the San Francisco 49ers on his 24th birthday.

Each week during the football season, we reach out to someone who covers Cal’s opponent and .pose 5 Questions. For the Bears’ ...

Here are the latest predictions, picks, and odds for the 2024 NFL Week 2 matchup between the San Francisco 49ers and the ...

Everything you need to know about the Rams' home game against the NFC West rival San Francisco 49ers, including start time, ...

Looking at Sunday’s San Francisco 49ers at LA Rams Week 3 NFL odds, lines and trends. Here’s what you need to know.

Two former 49ers players had strong words for San Francisco's defense after Sunday's 23-17 loss to the Vikings. Ex-cornerback Richard Sherman (a Niner from 2018-2020) and ex-safety Donte Whitner ...

The Minnesota Vikings (1-0) welcome the San Francisco 49ers (1-0) to U.S. Bank Stadium Sunday. Kickoff is set for 1 p.m. ET ...

The 49ers and Vikings had two of the Top 5 most impressive wins during Week 1 of the NFL season, but only one can come away 2 ...

Follow live reaction as the San Francisco 49ers overcame the absence of the injured Christian McCaffrey to comfortably beat ...