Christian McCaffrey is dealing with another long-term injury again. The San Francisco 49ers running back went down with a knee injury during the second quarter of the team's "Sunday Night Football ...

The spectacular touchdown gave Buffalo a 28-3 lead in the third quarter over the San Francisco 49ers. Buffalo had first-and-7 from the 7-yard line. Allen flicked a short pass to Cooper ...

Ward is one of several 49ers who has played through injury or personal tragedy during a trying season for San Francisco. Ward's 1-year-old daughter died on Oct. 28 but he has returned and played ...

San Francisco 49ers linebacker De'Vondre Campbell refused ... after missing multiple weeks to grieve the passing of his 1-year-old daughter. And thus, the frustrations of Campbell's teammates ...

The Los Angeles Rams beat the San Francisco 49ers 12-6, but the biggest story was 49ers LB De’Vondre Campbell exiting the game in the 2nd half by saying he “didn’t want to play”.

The San Francisco 49ers were barely hanging on in the playoff race, and desperately needed a win Thursday night against the Los Angeles Rams to stay afloat. And in the second half of a tight game ...

San Francisco 49ers' De'Vondre Campbell walks to the locker ... He's probably going get cut soon.” The 31-year-old Campbell signed a one-year, $5 million deal in the offseason with San Francisco ...

Deebo clearly needs to catch that ball." It was that type of game for the 49ers, who were held to their fewest yards (191) in a regular- season game in eight seasons under Shanahan and the fewest ...

But the three-time All-Big 12 QB, who broke 32 school records, was branded Mr Irrelevant after joining the San Francisco 49ers with the ... job since and No. 13 jerseys are a common sight in ...

The San Francisco 49ers will celebrate the NFL's Inspire Change initiative during "Thursday Night Football" this week against the Los Angeles Rams at Levi's® Stadium. The game will highlight the ...