Week 3 matchup vs. Rams with key injuries to McCaffrey, Samuel, and Kittle, testing their depth in this crucial NFC West ...

KRON4's Philippe Djegal reports. Read more here: <a href=" ...

The Vikings have had the 49ers’ number the past two years. One of the reasons Minnesota is 2-0 against San Francisco is the presence of defensive coordinator Brian Flores. Flores mixes things up ...

Terrell Owens belongs in any conversation regarding the greatest wide receivers ever. ‘T.O.’ ranks third in NFL history in ...

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Brock Purdy’s college reunion: Why 49ers’ opener vs. Jets has Iowa State flavor Purdy will face fellow Iowa State alums ...

The San Francisco 49ers will be without star running back Christian McCaffrey for a while. The 49ers are placing McCaffrey on injured reserve, a person familiar with the situation told USA TODAY ...

The San Francisco 49ers vs. Minnesota Vikings game will be ... it's a great time to stock up on the latest fan gear. Fanatics is our first stop for the newest in fan gear. The online fan gear ...

The San Francisco 49ers and Los Angeles Rams play on Sunday, Sept. 22, at SoFi Stadium in a game on the NFL Week 3 schedule. Which team will win the Week 3 NFL game? The 49ers are a 7.5-point ...

The game is scheduled to start at 8:15 p.m. EST and the ManningCast will be showing it on ESPN2. Fans looking to watch this ...

For those of you curious, there will be 21 Monday Night Football games in total, commented on by the duo of Joe Buck and Troy Aikman, who are extending their record as the longest broadcast paring in ...