Mutations that happen throughout a person’s life may contribute to disease more than we realized. In the summer of 2018, ...

By about 1900 the observations of Hertwig, Fol, and others were brought together to make the now-familiar picture: a single ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade ...

New work by Columbia researchers has turned a textbook principle of genetics on its head and revealed why some people who ...

Loss of the Y chromosome (LOY) in men, a dynamic mutation linked to aging, impairs immune function and increases risks of ...

How do mutations happen, and how do they influence the future of a species? Molecules of sickle-cell hemoglobin stick to one another, forming rigid rods. These rods cause a person's red blood ...

Researchers at Columbia University reveal how monoallelic expression (MAE) shapes genetic disease outcomes. By favoring one ...

A sperm cell and an egg cell each contain half the ... If one of a woman’s X chromosomes has the hemophilia mutation, she has a backup and will avoid most of the symptoms. But if she passes ...

New research reveals that certain cells inactivate one parent’s copy of a gene, leading to a bias in gene activity that may ...