Students isolate novel bacteriophage from the environment and characterize those phage using current research techniques including electron microscopy and DNA analysis. The genomic DNA from some of ...

When the phage genome is packaged into the capsid, a packaging ATPase pushes the DNA into the capsid, to high concentration, leading to pressures that are ten times higher than the pressure found ...

nucleic acid (DNA ... a phage behaves like a conventional human virus - the phage attaches itself to a bacterium and the replicates itself inside the host by injecting its genome into the host's ...

Immediately following injection into the host cell, the phage genome synthesizes early proteins that break down the host DNA, allowing the phage to take control of the cellular machinery. The phage ...

We studied 350,000 interactions and successfully identified the characteristics in the bacterial genome likely to predict phage efficacy," summarizes Aude Bernheim, last author of the study and Head ...

We studied 350,000 interactions and successfully identified the characteristics in the bacterial genome likely to predict phage efficacy ... analyzing the bacterial DNA. "This result exceeded ...

We studied 350,000 interactions and successfully identified the characteristics in the bacterial genome likely to predict phage efficacy." "Contrary to what we initially thought, the ability of ...

Insights into how diverse phage communities coexist within a single E. coli strain could lead to newer, more effective phage-based therapies.