According to a report from Adam Schefter of ESPN, the 49ers have ruled out running back Isaac Guerendo and offensive tackle Trent Williams from the lineup for Sunday's game against the Miami Dolphins.

He did not practice this week due to hamstring and foot injuries. Left tackle Trent Williams also was ruled out due to an ankle injury. Jaylon Moore will start for the fifth consecutive game in ...

All-Pro left tackle Trent Williams, who has missed the last four San Francisco games because of an ankle injury, is likely done for the season, 49ers coach Kyle Shanahan said Wednesday.

SANTA CLARA, Calif. — San Francisco coach Kyle Shanahan said the team is getting close to ruling out star left tackle Trent Williams for the rest of the season as his injured ankle isn't healing ...

"49ers coach Kyle Shanahan tells reporters that LT Trent Williams may not play again this season. 'I mean if he gets back to healthy we'd play him. But it's not like that right now. So it's ...

Shanahan did not specify Guerendo’s status for this Sunday’s game but gave a discouraging update for left tackle Trent Williams’ return. “If he could get back to healthy, we’d play him ...