BMJ1d
Rheumatoid arthritis, systemic lupus erythematosus and primary Sjögren’s syndrome shared megakaryocyte expansion in peripheral blood
Objectives Rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS) share many clinical manifestations and serological features. The aim of this study was to ...
BMJ2d
2018 Update of the EULAR recommendations for the management of large vessel vasculitis
Background Since the publication of the European League Against Rheumatism (EULAR) recommendations for the management of large vessel vasculitis (LVV) in 2009, several relevant randomised clinical ...
BMJ2d
EULAR evidence-based recommendations for the diagnosis of knee osteoarthritis
15 Department of Radiology. Leiden University Medical Centre, Leiden, The Netherlands 16 Department of Rheumatology and Clinical Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands ...
BMJ2d
Synovial macrophage M1 polarisation exacerbates experimental osteoarthritis partially through R-spondin-2
Correspondence to Professor Daozhang Cai and Dr Xiaochun Bai, Department of Orthopedics, Academy of Orthopedics - Guangdong Province, Orthopedic Hospital of Guangdong Province, The Third Affiliated ...
BMJ1d
Long-term effectiveness and safety of secukinumab for treatment of refractory mucosal and articular Behçet’s phenotype: a multicentre study
Objective To evaluate the effectiveness and safety of secukinumab in patients with a mucosal and articular Behçet’s phenotype resistant to conventional and biologic treatment. Methods A multicentre ...
BMJ2d
EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update
Background Since the publication of the EULAR recommendations for the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in 2016, several randomised clinical trials ...
BMJ1d
OP0023 GENERATION OF PT101, A HIGHLY SELECTIVE IL-2 MUTEIN FOR TREATMENT OF AUTOIMMUNE DISEASES
4 Pandion Therapeutics, Translational Sciences, Watertown, United States of America 5 Pandion Therapeutics, R&D, Watertown, United States of America Background: Regulatory T cells (Tregs) play a ...
BMJ5d
Gout: why is this curable disease so seldom cured?
3 Department of Rheumatology, University of Edinburgh, Centre for Molecular Medicine, Western General Hospital, Edinburgh, Scotland, UK 4 Department of Medicine, Rheumatology Section, Alicante ...
BMJ4d
Implementation of recommendations in rheumatic and musculoskeletal diseases: considerations for development and uptake
A clinical guideline is a document with the aim of guiding decisions based on evidence regarding diagnosis, management and treatment in specific areas of healthcare. Specific to rheumatic and ...
BMJ3d
The IL1-like cytokine IL33 and its receptor ST2 are abnormally expressed in the affected skin and visceral organs of patients with systemic sclerosis
1 Department of Anatomy, Histology and Forensic Medicine, University of Florence, Florence, Italy 2 Department of Biomedicine, Division of Rheumatology, AOUC, and Excellence Centre for Research, ...
BMJ6d
OP0132 TREAT-TO-TARGET APPROACH ALLOWS TO INDUCE SUSTAINED CLINICAL REMISSION IN OVER 60% OF PATIENTS WITH EARLY AXIAL SPONDYLOARTHRITIS
Background: Early therapeutic interventions in inflammatory rheumatic diseases have proven successful in inducing drug-free remission. However, such studies are difficult to conduct in axial ...
BMJ6d
POS0419 THE ROLE OF OROSOMUCOID 2 IN THE REGULATION OF BONE REMODELING BY INHIBITING OSTEOCLASTOGENESIS AND PROMOTING OSTEOGENESIS
1 Wonkwang University Medical School, Internal Medicine, Iksan, Korea, Rep. of (South Korea) 2 Jeonbuk National University Medical School, Internal Medicine, Jeonju, Korea, Rep. of (South Korea) ...