San Francisco tight end George Kittle speaks to reporters after the 49ers' 23-17 loss to the Minnesota Vikings on Sunday at U ...

The last time the Los Angeles Rams and San Francisco 49ers met, head coaches Sean McVay and Kyle Shanahan were without some ...

San Francisco 49ers quarterback Brock Purdy spoke about orchestrating the team's offense without playmakers Christian ...

The Minnesota Vikings will be without wide receiver Jordan Addison on Sunday when they host the San Francisco 49ers at U.S.

Dopp: This is my favorite prop of the slate. The Bengals need to get back on track after a slow start. It seems like we say ...

The last time the Rams and 49ers met, Sean McVay and Kyle Shanahan were without some starters. This time, star players will be absent yet again.

Star running back Christian McCaffrey sat out Week 1 while dealing with a calf injury and Achilles tendonitis. Coach Kyle ...

Just two games into the season, the Rams (0-2) are approaching desperate times as they prepare to face the San Francisco ...

Closing out Week 1 on Monday Night Football, Christian McCaffrey and the defending NFC-champion 49ers host the Jets in Aaron ...

Justin Jefferson, who hauled in a wild 97-yard touchdown catch in the first half, left the game early with a quad injury.

The San Francisco 49ers will soon begin their quest of defending their NFC crown and returning to the Super Bowl, with week ...