In a large-animal model study, researchers have found that heart attack recovery is aided by injection of heart muscle cell spheroids derived from human induced pluripotent stem cells, or hiPSCs, that ...

In a large-animal model study, researchers have found that heart attack recovery is aided by injection of heart muscle cell ...

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has developed a comprehensive set of innovative genetic tools and mouse lines ... or in disease models," said Dr. Irene ...

A new gene therapy can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the heart can pump and dramatically improves ...

Heart failure has historically been irreversible, but the outcome of a new study suggests that could someday change. At the University of Utah, scientists used a new gene therapy that was shown to ...

2024 — Researchers have reduced scar formation and improved heart function in mouse models of heart failure using a monoclonal antibody treatment, similar to that approved by the FDA to treat other ...

Previous attempted therapies for heart failure have shown improvements to heart function on the order of 5-10%. cBIN1 gene therapy improved function by 30%. "It's night and day," Shaw adds.