EurekAlert!1d
12,000-year old stones may be very early evidence of wheel-like technology
A collection of perforated pebbles from an archaeological site in Israel may be spindle whorls, representing a key milestone ...
ahajournals.org1mon
YAP Overcomes Mechanical Barriers to Induce Mitotic Rounding and Adult Cardiomyocyte Division
Sarcomere disassembly is required for cardiomyocyte progression from S to G2 phase and the induction of mitotic rounding. Although oscillatory Cdk expression was induced in YAP5SA cardiomyocytes, ...
eLife6y
Mitotic progression, arrest, exit or death relies on centromere structural integrity, rather than de novo transcription
Transcription was also proposed to sustain a robust spindle assembly checkpoint (SAC ... However, we were unable to detect significant changes in mitotic transcript levels. Moreover, inhibition of ...
eLife9y
Mechanical design principles of a mitotic spindle
In cells that have a nucleus, a structure called the mitotic spindle ensures that chromosomes are partitioned equally between the dividing cells. The spindle consists of long, thin protein fibers ...