People with multiple sclerosis (MS) often stop taking disease-modifying ... patients tend to experience fewer relapses and less disease activity but show more evidence of neuronal degeneration.

Is multiple sclerosis truly a “neuronal disease” as the book title ... given that little is known about the molecular basis of cortical atrophy and lesions, which are detected with increasing ...

The pathophysiology of multiple sclerosis (MS) is characterized by demyelination, which culminates in a reduction in axonal transmission. Axonal and neuronal degeneration seem to be concomitant ...

Targeting ceramide synthase enzymes may reduce multiple sclerosis severity by limiting ceramide C16 synthesis, offering ...

Multiple sclerosis, a neuroinflammatory disease that affects nearly 3 million people worldwide, causes a loss of myelin, the ...

Background: Multiple sclerosis is a chronic inflammatory disease ... [20] In these patients, cognitive function improved and the brain atrophy rate was significantly slowed. Here, immunomodulatory ...

Drugmakers had hoped that inhibiting receptor-interacting protein kinase would decrease inflammation and reduce neuronal degeneration in patients with multiple sclerosis and other neurodegenerative co ...

B cells are a type of white blood cell. They make antibodies -- proteins that fight viruses and bacteria. B cells normally can’t cross from your blood into your brain or spinal cord. If you have ...

Oct. 17, 2024 — In a study of commonly used treatments for multiple sclerosis, both medical and behavioral interventions, and a combination of the two, resulted in significant improvements in ...

Scientists have identified a relationship between ancient viral DNA and susceptibility to neurodegenerative diseases like ...

Mapping cell types in MS lesions reveals unique tissue niches and interactions, offering insights into the molecular drivers of multiple sclerosis progression.

Oct. 17, 2024 — In a study of commonly used treatments for multiple sclerosis, both medical and behavioral interventions, and a combination of the two, resulted in significant improvements in ...