Motor neuron diseases are a group of progressive and ultimately fatal neurodegenerative disorders of the motor system, ...

HYNR-CS-Allo is under clinical development by Corestemchemon and currently in Phase I for Multiple System Atrophy (MSA or Shy-Drager Syndrome or Multi-System Degeneration). According to GlobalData, ...

Amyotrophic lateral sclerosis (ALS) is a progressive and fatal motor neuron degenerative disease characterised by ... cell death and modulation of stress granule formation across multiple stress ...

In PSP, there is gross midbrain atrophy and neuronal loss, gliosis and abundant neurofibrillary tangles and neuropil threads in many brain regions. There is a uniform presence of tau-positive ...

Sanofi said an oral treatment for multiple sclerosis, tolebrutinib, met its key goal in a Phase 3 study, potentially clearing the way for regulatory approval, although in two other studies ...

Background: Biomarkers can be used to assess the severity of spinal muscular atrophy (5q SMA; SMA ... Four biomarkers were included: survival motor neuron 2 (SMN2) copies, neuronal apoptosis ...

In immunotherapy trials, MRI volume loss does not correlate with degeneration. It does correlate with removal ... Anti-inflammatory treatments for multiple sclerosis initially shrink the brain, too, ...

specifically multiple sclerosis (MS). For many years, however, the mechanism behind this dysfunction has remained unclear. In a new Yale-led study, a team of researchers finds that this loss of ...

The symptoms of amyotrophic lateral sclerosis (ALS)—a neurodegenerative ... from a quiescent state to a biochemical storm causing neuronal death. One hypothesized trigger is dysfunction of ...

Generally, evidence notes that hypersexuality with multiple sclerosis (MS) is uncommon. A 2024 review investigating hypersexuality in neurological disorders wanted to include MS, but did not as ...