These benefits contribute to improved efficacy of the drug product in patient outcomes. One polymer stands out as being uniquely designed for use in osmotic pump tablets: POLYOXâ„¢ polyethylene oxide.
Compared with polymer NPs, albumin NPs are more biocompatible ... and NP carriers with surface modifications such as PEG, IM, and biomimetic membranes. The advantages of using NP carriers to treat ...
To mitigate and to regulate the formation of a protein corona, NPs are usually coated with polymers designed to avoid nonspecific interactions, forming the so-called coating. Poly (ethylene glycol) ...
In the search for alternatives to PEG, zwitterionic polymers have attracted the most attention. These polymers have equal numbers of positively and negatively charged ion groups along their molecular ...
NPs vary regarding their fate and may be trapped in the terminal circulatory system of the brain. However, the available data is inadequate regarding the fate of the biodegradable polymer NPs.
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PEG-Naloxol (NKTR-118) in Phase II clinical trials. Clinical benefit has already been demonstrated with polymer–drug conjugates bearing classical chemotherapeutic agents. The future of cancer ...
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