The study demonstrates that activating the vitamin D receptor (VDR) with calcitriol suppresses cell proliferation in ...
Pulmonary arterial hypertension (PAH) is a vascular remodeling disease that pathologically increases pulmonary vascular resistance. Ultimately, this leads to right ventricular failure and ...
Indeed, it is possible that inflammation may initiate vascular remodeling (ie ... NK = natural killer; PAH =pulmonary arterial hypertension; PASMC = pulmonary artery smooth muscle cell; RANTES ...
Introduction: Pulmonary arterial hypertension (PAH ... elements are key features contributing to vascular remodeling. Integrins, members of the cell adhesion receptor superfamily, are known to promote ...
Introduction: Pulmonary arterial hypertension (PAH) is a progressive and fatal disease characterized by pulmonary artery (PA) remodeling. Extensive proliferation of PA smooth muscle cells (PASMCs) is ...
TX45 aims to address the physiological abnormalities of PH-HFpEF through its effects on both pulmonary and systemic vasodilation, cardiac diastolic dysfunction and potential remodeling in ... several ...
Tectonic Therapeutic to present positive phase 1a results of TX45, a long-acting, Fc-relaxin fusion protein at AHA 2024: Watertown, Massachusetts Tuesday, November 12, 2024, 13:00 ...
Patients who receive pulmonary artery catheters (PACs) after cardiac surgery have significantly reduced risk for 1-year mortality.
As the rollout of its recently launched pulmonary arterial hypertension (PAH) drug Winrevair ramps up, Merck is continuing its work to improve awareness of and education around the rare disease.
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STATEN ISLAND, N.Y. — Northwell Staten Island University Hospital (SIUH) in Ocean Breeze has become the first medical facility in the United States to treat acute pulmonary embolism (PE) using the ...