Research into prostacyclin analogs for the treatment of WHO Group 2 PH has been limited ... Phosphodiesterase type 5; PH: Pulmonary hypertension.
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[105] This trial enrolled 405 PAH patients (a majority were WHO functional class II and III) and randomized them to placebo or tadalafil 2.5, 10, 20, or 40 mg daily for 16 weeks. Compared with ...
Of the 50 patients with isolated PAPVD, 47 underwent right heart catheterisation (RHC), mean values: mean pulmonary arterial pressure (mPAP) 36.5 (±15) mmHg, pulmonary arterial wedge pressure (PAWP) ...
A pooled analysis of two prior trials suggests patients with a variety of cardiac index scores saw improvement when Winrevair ...
The woman was suffering from Eisenmenger syndrome, a condition that occurs when a congenital heart defect causes abnormal blood circulation, resulting in pulmonary hypertension and lung damage. "As ...
Keros Therapeutics has halted dosing in two of the three treatment arms of a phase 2 trial of its pulmonary arterial ...
a Phase 2 clinical trial of cibotercept (KER-012) in combination with background therapy in patients with pulmonary arterial hypertension ("PAH"), based on a safety review due to the unanticipated ...
CAMPHOR and PAH-SYMPACT are the most reliable QOL tools for PAH, with Grade A ratings for internal reliability. LPHQ and ...
a Phase 2 clinical trial of cibotercept (KER-012) in combination with background therapy in patients with pulmonary arterial hypertension ("PAH"), based on a safety review due to the unanticipated ...
The company said the unanticipated events of pericardial effusion--when fluid builds up in the space around the heart--came in the Phase 2 clinical trial of 3 milligrams per kilogram and 4.6 mg/kg ...
Lipodermatosclerosis (LDS) was observed in 4.4% of patients with systemic sclerosis (SSc) and was associated with pulmonary hypertension (PH), according ... or died whereas 115 patients without LDS ...