Brock Purdy has faced the Vikings twice in his career. In both games, he turned the ball over twice, led the 49ers to just 17 ...

San Francisco 49ers quarterback Brock Purdy will be tested in the coming weeks with the absence of key offensive weapons.

San Francisco 49ers star tight end George Kittle missed his second straight practice on Friday as ESPN insider Adam Schefter ...

San Francisco 49ers starting center Jake Brendel has the worst pass-blocking grade in the NFL through two weeks, according to ...

The rookie, who has made all his field goals and extra points in two games, injured his groin during last weekend’s loss to ...

Jimmy Garoppolo knows what it feels like as a San Francisco 49er to come to L.A., but now the quarterback is on the other ...

NFL Week 3 odds, picks, predictions, TV and streaming information for the Sunday football game between the San Francisco ...

In June, Jefferson signed a record-setting deal with Minnesota. The four-year, $140 million contract extension made Jefferson ...

The Minnesota Vikings and the San Francisco 49ers square off today in a NFL Week 2 showdown. Find out how to watch.

San Francisco 49ers' George Kittle is listed as doubtful for Sunday's game against the Rams. He joins Christian McCaffrey and ...

When Christian McCaffrey went down, the 49ers could take solace in the fact that they had another versatile and dynamic ...

ET/10 a.m. PT The San Francisco 49ers will visit the Minnesota Vikings this Sunday, Sept. 15, airing live at 1 p.m. ET on CBS ...