A genetic quirk protects some people from norovirus. Can vaccines …
Mar 7, 2024 · Researchers at the University of North Carolina believe that if a suitably broad norovirus vaccine is administered to children who are around six months old, the jab could then guide the...
Vaccine study demonstrates protection against norovirus illness
An experimental norovirus vaccine provided significant protection against both viral infection and its associated gastrointestinal illness in a study of nearly 80 subjects, said a consortium of researchers led by Baylor College of Medicine in the current …
IDWeek 2024: Moderna’s norovirus vaccine mRNA-1403 shows …
Oct 21, 2024 · At IDWeek 2024, Moderna presented interim results from an ongoing Phase I/II, randomised, observer-blind, placebo-controlled, dose-ranging trial (NCT05992935) for mRNA-1403, a prophylactic vaccine candidate under investigation for norovirus (NoV) infections.
Norovirus: Could vaccine for winter vomiting bug be near?
Nov 14, 2024 · There is currently no licensed vaccine for norovirus – commonly known as the winter vomiting bug – but are scientists getting closer to finally finding a jab that works? Volunteers are being...
Norovirus Vaccines: Current Clinical Development and Challenges
Noroviruses are the major viral pathogens causing epidemic and endemic acute gastroenteritis with significant morbidity and mortality. While vaccines against norovirus diseases have been shown to be of high significance, the development of a broadly ...
Bivalent norovirus mRNA vaccine elicits cellular and humoral …
Oct 1, 2024 · Nucleoside-modified mRNA-LNP vaccines have revolutionized vaccine development against infectious pathogens due to their ability to elicit potent humoral and cellular immune responses. In this...
The State of Norovirus Vaccines - PMC
While there is currently no approved norovirus vaccine, recent human clinical efficacy trials with virus-like particle–based vaccines have shown promise. Several additional norovirus vaccine platforms are also currently under development and will ...
Norovirus: Vaccine to be trialled for vomiting bug - BBC News
Oct 22, 2024 · A vaccine is to be trialled on thousands of people to find out if it could protect against norovirus - a stomach bug that causes vomiting and diarrhoea.
Norovirus Vaccines: Current Clinical Development and Challenges
Dec 19, 2021 · This short article reviews the recent progress in norovirus vaccine development, focusing on those from recent clinical studies, as well as summarizes the barriers that are being encountered in this developmental process and discusses issues of future perspective.
Recent advances in human norovirus research and implications …
We review recent advances in molecular epidemiology of noroviruses, immunology, and in-vitro cultivation of noroviruses using human intestinal enteroids. We also provide an update on the status of norovirus vaccine candidates.