Colchicine in Cardiovascular Disease: In-Depth Review
Dec 29, 2021 · There is broad evidence about colchicine’s benefits in acute and recurrent pericarditis, and emerging indications for its use in postprocedural AF, CAD, and stroke on the basis of its targeting of cardiovascular inflammation. Indeed, colchicine may potentially become an important addition to other standard cardiovascular therapies.
Colchicine’s Role in Cardiovascular Disease Management
Mar 21, 2024 · Randomized clinical trials established low-dose colchicine as an effective treatment for pericarditis and atherosclerotic cardiovascular disease. The mechanisms through which colchicine exerts its beneficial anti-inflammatory and cardiovascular effects remain an area of vigorous investigation.
Colchicine in Patients with Chronic Coronary Disease
Aug 31, 2020 · Evidence from a recent trial has shown that the antiinflammatory effects of colchicine reduce the risk of cardiovascular events in patients with recent myocardial infarction, but...
Update on the Role of Colchicine in Cardiovascular Disease
Feb 10, 2024 · Colchicine is an effective anti-inflammatory therapy in the prevention of acute coronary syndrome. Ongoing studies aim to assess when, and in whom, colchicine is most effective to prevent cardiovascular events in patients …
Colchicine in Acute Myocardial Infarction - New England Journal …
Nov 17, 2024 · Inflammation is associated with adverse cardiovascular events. Data from recent trials suggest that colchicine reduces the risk of cardiovascular events. In this multicenter trial with a 2-by-2...
Colchicine in Cardiovascular Disease: In-Depth Review
Jan 4, 2022 · We aim to summarize colchicine's pharmacodynamics and the mechanism behind its anti-inflammatory effect, outline thus far accumulated evidence on treatment with colchicine in cardiovascular disease, and present ongoing randomized clinical trials.
FDA Approves First Anti-Inflammatory Drug for ... - Healthline
Jul 30, 2023 · Called LODOCO (colchicine, 0.5mg), the recently approved medication has been shown to reduce cardiac event risk in adults with atherosclerotic cardiovascular disease (ASCVD) or with multiple...
Colchicine in ischemic heart disease: the good, the bad and the …
Colchicine mechanism of action—colchicine primarily causes tubulin disruption and prevents microtubule formation, thus resulting in neutrophils inhibition, antinflammatory effects, beneficial cardiovascular effects and inhibiting endothelial cells proliferation.
Therapeutic potential of colchicine in cardiovascular medicine: a ...
Jan 19, 2022 · Based on its unique efficacy as an anti-inflammatory agent, colchicine has been used in the therapy of cardiovascular diseases including coronary artery disease, atherosclerosis, recurrent...
The Use of Colchicine in Cardiovascular Diseases: A Systematic Review
Feb 16, 2021 · Colchicine has anti-inflammatory properties that alter neutrophil function and pro-inflammatory substances. Several trials support the use of colchicine in inflammatory pericardial disease. More recently, colchicine has been shown to …