Retinol-Containing Graft Copolymers for Delivery of Skin-Curing …
WEBAug 2, 2019 · A strategy combining the controlled atom transfer radical polymerization (ATRP) and the Cu(I) catalyzed 1,3-dipolar azide-alkyne cycloaddition (CuAAC) was applied in the synthesis of amphiphilic graft copolymers with hydrophilic side chains, e.g., P((HEMA-graft-PEG)-co-MMA).
Retinol-Containing Graft Copolymers for Delivery of Skin
WEBAug 2, 2019 · The designed amphiphilic graft copolymers P ( (HEMA- graft -PEG)- co -MMA), showing tendency to micellization in aqueous solution at room temperature, were encapsulated with arbutin (ARB) or vitamin C (VitC) with high efficiencies (>50%).
PEG Graft Polymer Carriers of Antioxidants: In Vitro Evaluation for ...
WEBDec 3, 2020 · The evaluated PEG graft copolymers are promising safe carriers for the transdermal delivery of active substances, e.g., antioxidants, including skin therapy in cosmetology.
1 H-NMR spectra of (a) HEMA, and (b) after its ... - ResearchGate
WEBMoreover, P((HEMA–graft–PEG)–co–MMA) graft copolymers were prepared by combining the pre-polymerization modification of HEMA and a “click” reaction using a “grafting onto” approach.
4-n-Butylresorcinol-Based Linear and Graft Polymethacrylates for ...
WEBFeb 5, 2020 · This creates a grafted copolymer P((HEMA–graft–PEG)–co–MMA) with amphiphilic properties and the ability to undergo micellization and encapsulate active substances.
4- n-Butylresorcinol-Based Linear and Graft Polymethacrylates …
WEBFeb 5, 2020 · Moreover, P((HEMA-graft-PEG)-co-MMA) graft copolymers were prepared by combining the pre-polymerization modification of HEMA and a "click" reaction using a "grafting onto" approach. All copolymers could form micelles with encapsulated active substances (vitamin C (VitC), vitamin E (VitE), arbutin (ARB)), which are …
Pharmaceutics | Free Full-Text | PEG Graft Polymer Carriers of
WEBDec 3, 2020 · PEG graft copolymers P((HEMA-graft-PEG)-co-MMA) and P((HEMA-graft-PCL)-co-MPEGMA) for micellar systems loaded with the active substance, i.e., ARB, and the conjugates varied with the “click” active substance such as P((HEMA-click-FA)-co-MPEGMA) and P((HEMA-click-LA)-co-MPEGMA) were synthesized . The active substances are classified as ...
PEG Graft Polymer Carriers of Antioxidants: In Vitro Evaluation for ...
WEBDec 3, 2020 · Previously designed amphiphilic graft copolymers with retinol or 4-n-butylresorcinol functionalized polymethacrylate backbone and poly (ethylene glycol) (PEG) side chains that included...
Characteristics of "click" graft copolymers P((HEMA-graft-PEG…
WEB... creates a grafted copolymer P ( (HEMA-graft-PEG)-co-MMA) with amphiphilic properties and the ability to undergo micellization and encapsulate active substances.
Preparation and properties of PEG-modified PHEMA hydrogel and …
WEBNovel HEMA based hydrogels modified by a PEG graft were prepared by the crosslinking polymerization of HEMA in the presence of a methacryloyl PEG macromer with different chain length.