Microgel assembly: Fabrication, characteristics and application in ...
Mar 1, 2022 · Microgel assembly, a macroscopic aggregate formed by bottom-up assembly of microgels, is now emerging as prospective biomaterials for applications in tissue engineering and regenerative medicine (TERM). This mini-review first summarizes the fabrication strategies available for microgel assembly, including chemical reaction, physical reaction ...
Guest–host interlinked PEG-MAL granular hydrogels as an …
PEG microgels were used to assemble a densely packed granular system with an intrinsic interstitium-like negative space. In this material, guest–host molecular interactions provide reversible non-covalent linkages between discrete PEG microgel particles to …
Recent Advances in Microgels: From Biomolecules to Functionality
Aqueous two-phase systems (PEG and dextran) have been used to template collagen microgels. Collagen droplet contraction rates depend on cell density and the presence of growth factors. The diffusion of growth factors in collagen microgels is faster than that in …
Assembly of PEG Microgels into Porous Cell-Instructive 3D …
Here, norbornene-bearing poly (ethylene glycol) (PEG) based microgels were assembled into 3D cell-instructive scaffolds using a PEG-dithiol linker and thiol-ene click photopolymerization. The bulk modulus of these materials depended primarily on the crosslink density of …
Assembly of PEG Microgels into Porous Cell-Instructive 3D ... - PubMed
Here, norbornene-bearing poly(ethylene glycol) (PEG) based microgels are assembled into 3D cell-instructive scaffolds using a PEG-dithiol linker and thiol-ene click photopolymerization. The bulk modulus of these materials depends primarily on the crosslink density of …
Microfluidic fabrication of polyethylene glycol microgel …
The microfluidic technique applied here allows production of PEG-based microgel capsules with tunable dimensions, shell thickness and density, and degradation rate. We demonstrate the retention and release of fluorescently labelled dextran (MW = …
Microparticle Hydrogel Material Properties Emerge from Mixing …
Oct 30, 2023 · The data presented herein suggests that mixing-induced homogenization of a PEG-dextran ATPS principally influences the polymer concentration and cross-link density of its PEG microgel products during the early stages of phase separation.
Functionalized Microgel Rods Interlinked into Soft Macroporous ...
Jan 14, 2022 · The microgel rods are fabricated by plug-flow microfluidics and photoinitiated free-radical polymerization of 8-arm star-PEG-acrylate (sPEG-AC). The microgels are functionalized with either reactive epoxy groups or primary amines during polymerization on-chip by the addition of glycidyl methacrylate (GMA) or 2-aminoethyl methacrylate (AMA ...
Pathways and challenges towards a complete characterization of ... - Nature
Sep 4, 2020 · Here we describe pathways toward a complete understanding of microgel colloids based on recent experimental advances in nanoscale characterization, such as super-resolution microscopy,...
Microgel assembly: Fabrication, characteristics and application in ...
Microgel assembly, a macroscopic aggregate formed by bottom-up assembly of microgels, is now emerging as prospective biomaterials for applications in tissue engineering and regenerative medicine (TERM). This mini-review first summarizes the ...