PCL-PEG copolymer based injectable thermosensitive hydrogels
WEBPCL-PEG-based thermoresponsive injectable hydrogels have been proven as efficient carrier systems for various biomedical applications because of their ease of formulation, amphiphilic nature, better stability in biological milieu, enhanced cargo loading, and excellent biocompatibility.
Biodegradable diblock copolymeric PEG-PCL nanoparticles: …
WEBOct 20, 2020 · The PEG portion in diblock copolymers of PEG-PCL enhances biocompatibility and PCL polyester part promotes degradation of the cargo complex. To obtain different types of PEG-PCL diblock copolymers, different available procedures have been described in terms of reactants and catalysts.
PEG-PCL-based nanomedicines: A biodegradable drug
WEBAug 28, 2017 · Nanoscale drug delivery systems based on poly (ethylene glycol)-poly (ε-caprolactone) copolymers (PEG-PCL) represent a strategy to implement therapies with enhanced drug accumulation at the site of action and decreased off-target effects.
Synthesis, characterization, and crystallization behaviors of poly
WEBFeb 27, 2020 · The PDLA-PEG-PDLA triblock copolymers were synthesized by ring-opening polymerization (ROP) of D -lactide using PEG as an initiator and stannous octoate as a catalyst 26. The synthetic...
Recent Advances on PEO-PCL Block and Graft Copolymers as …
WEBMar 13, 2023 · Angiopep-conjugated PEG-PCL nanoparticles exhibited increased tumor penetration, accumulation, and successful decrease of tumor cells. In another anticancer formulation containing doxorubicin, PEG-PCL core-corona nanoparticles were employed and decorated with hyaluronic acid (HA-PEG-PCL).
PCL-PEG copolymer based injectable thermosensitive hydrogels
WEBMore specifically, the PCL is coupled with polyethylene glycol (PEG) to obtain amphiphilic thermosensitive "smart" copolymers (PCL-PEG), to form rapid and reversible physical gelation behavior.
Multi-Stimulus-Responsive Shape-Memory Polymer Nanocomposite Network ...
WEBFeb 3, 2015 · In this study, we developed a thermoresponsive and water-responsive shape-memory polymer nanocomposite network by chemically cross-linking cellulose nanocrystals (CNCs) with polycaprolactone (PCL) and polyethylene glycol (PEG).
Synthesis, characterization and application of reversible PDLLA-PEG …
WEBJan 11, 2016 · In this study, a series of injectable thermoreversible and thermogelling PDLLA-PEG-PDLLA copolymers were developed and a systematic evaluation of the thermogelling system both in vitro and...
Long-Term Evaluation of Dip-Coated PCL-Blend-PEG Coatings in …
WEBMar 24, 2020 · Our study focused on the long-term degradation under simulated conditions of coatings based on different compositions of polycaprolactone-polyethylene glycol blends (PCL-blend-PEG), fabricated for titanium implants by a dip-coating technique.
PEG-PCL-based nanomedicines: A biodegradable drug delivery ... - PubMed
WEBAug 28, 2017 · Nanoscale drug delivery systems based on poly (ethylene glycol)-poly (ε-caprolactone) copolymers (PEG-PCL) represent a strategy to implement therapies with enhanced drug accumulation at the site of action and decreased off-target effects.
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